Neurobinar Julie Koenig Gambini (INMED), Florence RICCARDI (MMG), and Manon Chateaux (ISM)

Mardi 24 Mai à 13h sur Zoom

Enregistrement requis: Neurobinar #14 : May 24th at 1pm on Zoom | NeuroMarseille (neuro-marseille.org)

Coding distance in the hippocampus: circuits and mechanisms by Julie Koenig Gambini

Julie Koenig Gambini is a maître de conférences in the team of Jérôme Espztein at INMED in Marseille. She is studying the neurophysiological correlates of space and memory in the brain, with the aim of understanding the biological mechanisms of navigation. Julie Koenig Gambini studied psychology at Louis Pasteur university (Strasbourg) and did her PhD in the field of spatial cognition. During her thesis, she studied the involvement of the medial septum, a tiny brain nucleus, in the encoding, consolidation and recall of spatial information in rats. She then turned to in vivo electrophysiology to record place and grid cells that are spatially modulated neurons located in the hippocampus and medial entorhinal cortex, respectively. Her post-doctoral work in the team of Stefan leutgeb at UCSD, proved, for the first time in adult rats, that grid cells are not a prerequisite for the spatial modulation of place cells. She then moved to Seoul, in the lab of Sebastien Royer, where she studied how reward information are encoded in hippocampal networks. In 2014, she moved back to Europe, in Marseille, in the team of Jérôme Epsztein and is now studying how place cells integrate two streams of information (external and internal cues). In 2019, they published the first French paper using virtual reality in rodents showing that the hippocampal spatial map is not homogeneous, but that its resolution could be increased locally in areas rich in proximal visual cues.

Therapeutic development for KCNQ2-related Developmental and Epileptic Encephalopathies (DEE) by Florence Riccardi

Florence holds a doctorate in medicine and a specialization in medical genetics at Aix-Marseille University. After her residency, she did a fellowship in the Medical Genetics department of the children’s hospital La Timone in Marseille. Currently, she is a part-time consultant in clinical genetics at the medical genetics department of the Sainte Musse Hospital in Toulon. Regarding scientific background, Florence obtained a Master’s degree in Genetics at the University Paris-Diderot in 2017. She has chosen to start a PhD in human neurogenetics in parallel with her clinical activities in 2020. Her PhD focuses on the development of RNA interference therapy in KCNQ2-related developmental and epileptic encephalopathies under the supervision of Laurent Villard (MMG, U1251 Inserm). She is also particularly interested in identifying the causes of autism and intellectual disability.

The sensorimotor loop underlying phantom hand movements in transhumeral amputees by Manon Chateaux

Manon is a 2019 graduate of ENS Paris-Saclay. She obtained her master’s degrees in cellular neuroscience and biomedical engineering in collaboration with Sorbonne University and ESPCI Paris Tech respectively. Currently, she is a PhD student at ISM (Institut des Sciences du Mouvement) under the supervision of Jozina De Graaf. She is studying phantom hand movement in transhumeral amputees using MEG and fMRI to better understand the underlying sensorimotor loop and why phantom movements are reported to be particularly slow and to require demanding effort.