Séminaire de Franck Debarbieux 15/11/2024

Vendredi 15 novembre 2024, 14h30 – Salle Henri Gastaud, INT

Franck Debarbieux (INT)

Preclinical 2P microscopy: from characterizing pathological neuroinflammation to understanding the restorative effect of light and electric fields on the CNS

Abstract: Since 2014, INT’s IMAPATH team has established and characterized an original line of multifluorescent mice to study neuroinflammatory processes, while promoting 2P spectral microscopy as an exceptional preclinical imaging modality. Our methodological efforts to longitudinally visualize and characterize the recruitment of individual immune cells in situ in the same animal have led to fundamental observations on their phenotypic evolution in the pathological CNS. By presenting a sel